Decamethoxin
化學名稱:N1,N10-bis(2-((2-isopropyl-5-methylcyclohexyl)oxy)-2-oxoethyl)-N1,N1,N10,N10-tetramethyldecane-1,10-diaminium chloride
化學式: C38H74Cl2N2O4
Cas#: 38146-42-8
Exact Mass: 692.50
分子量: 693.92
m/z: 692.50 (100.0%), 694.50 (63.9%), 693.51 (41.1%), 695.50 (26.3%), 696.50 (10.2%), 694.51 (8.2%), 696.51 (4.4%), 697.50 (4.2%)
Elemental Analysis: C, 65.77; H, 10.75; Cl, 10.22; N, 4.04; O, 9.22
Decamethoxin Standard：
|
Parameter |
Standard |
Method |
result |
|
Description |
White, fine-crystalline powder with light specific smell |
Visual |
Yes
|
|
Solubility |
Easily soluble in water P and 96% alcohol P |
Accordingly to EP |
Yes
|
|
Definition |
B. Specific optical rotation from -480 to -510 C. Point of fusion from 1630 C to 1680C (with decomposition) D. Chloride reaction (a) E. Menthol with vanillin reagent P reaction in sulfuric acid P F. Ester group reaction with hydroxide amine alkaline solution P and ferric (III) chloride solution P |
EP, p.2.2.7.
EP, p.2.2.14
EP, P.2.3.1 Chemical
Chemical |
B. Specific optical rotation -50.05°，yes C. Melting point 164.6℃-167.0℃，yes D. Chloride reaction (a) ：yes E. Menthol with vanillin reagent P reaction in sulfuric acid P:yes F. Ester group reaction with hydroxide amine alkaline solution P and ferric (III) chloride solution P:yes |
|
Transparence |
Solution S must be clear or not to exceed the Standard solution I by the level of opacity |
EP, P.2.2.1 |
Yes
|
|
Coloring degree |
Solution S must be colorless |
EP, P.2.2.2, method II |
Yes
|
|
pH |
From 5,5 to 7,5 |
EP, p.2.2.3 |
7.22 |
|
Specific optic rotation |
From - 48,0? to -51,0? calculated to the dry substance |
EP, p.2.2.7 |
-50.05° |
|
Impurities |
A. Menthyl ether of chloracetic acid, not more than 0,25% B. Tetramethyldiamine-decan –not more than 0,4% |
TLC |
A:0.1% B:0.1% |
|
Residual quantities of organic solvents |
Acetone not more than 0,2 % Ethylacetate not more than 0,2 % |
GC |
Not detected |
|
Mass loss after drying |
Not more than 4,5 % |
EP, p.2.2.32 |
1.0% |
|
Sulfate ash |
Not more than 0,1 % |
EP, p.2.4.14 |
0.06% |
|
Heavy metals |
<10 ppm |
EP, p.2.2.8, method A |
Yes |
|
Assay |
Not less than 99,0 % calculated to the dry substance |
Titration |
99.12% |
|
Microbiological purity |
1 g. of substance contains not more than 100 microorganisms, including fungi |
EP, p.2.6.12 |
Yes
|
